Nutr Rev. 2009 Jan;67(1):49-56.
Pomegranate juice: a heart-healthy fruit juice.
Pomegranate juice is
a polyphenol-rich fruit juice with high antioxidant capacity. In
limited studies in human and murine models, pomegranate juice has been
shown to exert significant antiatherogenic, antioxidant,
antihypertensive, and anti-inflammatory effects. Pomegranate juice
significantly reduced atherosclerotic lesion areas in immune-deficient
mice and intima media thickness in cardiac patients on medications. It
also decreased lipid peroxidation in patients with type 2 diabetes, and
systolic blood pressure and serum angiotensin converting enzyme
activity in hypertensive patients. Thus, the potential cardioprotective
benefits of pomegranate juice deserve further clinical investigation,
and evidence to date suggests it may be prudent to include this fruit
juice in a heart-healthy diet.