Number of included patients:
- Neurosurgery. 2006 Jul;59(1):E206; discussion E206.
Primary melanocytic tumor of the cerebellopontine angle mimicking a vestibular schwannoma: case report.
Piedra MP, Scheithauer BW, Driscoll CL, Link MJ.
Department of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota 55901, USA.
The majority of tumors of the cerebellopontine angle (CPA) are benign.
We report the case of a primary malignant melanoma of the CPA that
mimicked a vestibular schwannoma (acoustic neuroma). We discuss the
differential diagnosis and prognosis of melanotic lesions at this
CLINICAL PRESENTATION: A 49-year-old man presented with a
7-year history of unilateral deafness and a several month history of
imbalance, intractable nausea and vomiting, as well as weight loss. A
neurological work-up revealed a large tumor in the left CPA
radiographically diagnosed as a vestibular schwannoma.
translabyrinthine approach revealed a pigmented, vascular neoplasm
encasing vessels and cranial nerves of the left CPA. The tumor was
subtotally resected, and a histopathological diagnosis of melanoma was
made. The patient had no history of cutaneous melanoma and no other
site of disease was ever discovered.
CONCLUSION: This case most likely
represents primary melanoma of the central nervous system that mimicked
a vestibular schwannoma. The differential diagnosis of melanotic
lesions of the CPA is discussed as are the prognostic implications of