Int J Oral Maxillofac Surg. 2006 Aug;35(8):767-71. Epub 2006 Mar 31
Primary malignant schwannoma of the cervical plexus with melanocytic differentiation.
malignant schwannomas are rare neoplasms of nerve sheath origin,
especially in the location of the head and neck where few cases are
described in the literature. These tumours may pose a diagnostic
dilemma in the work-up of a neck mass. The case presented here is of a
malignant schwannoma that originated in the cervical plexus with the
rare histological feature of melanocytic differentiation.
Histopathological examination with immunostaining techniques is
essential for the diagnosis of these tumours. The management of these
neoplasms is still controversial, although the treatment of choice is
radical surgical excision of the lesion. The role of postoperative
radiotherapy or chemotherapy is not clear, although some authors
recommend its use to prevent local recurrence, for unresectable
recurrent tumours or in cases of distant metastases.