Clinical applications of magnetic nanoparticles for hyperthermia.

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Int J Hyperthermia. 2008 Sep;24(6):467-74.
Clinical applications of magnetic nanoparticles for hyperthermia.
Thiesen B, Jordan A.MagForce Nanotechnologies AG, Berlin, Germany.

fluids are increasingly used for clinical applications such as drug
delivery, magnetic resonance imaging and magnetic fluid hyperthermia.
The latter technique that has been developed as a cancer treatment for
several decades comprises the injection of magnetic nanoparticles into
tumors and their subsequent heating in an alternating magnetic field.
Depending on the applied temperature and the duration of heating this
treatment either results in direct tumor cell killing or makes the
cells more susceptible to concomitant radio- or chemotherapy. Numerous
groups are working in this field worldwide, but only one approach has
been tested in clinical trials so far. Here, we summarize the clinical
data gained in these studies on magnetic fluid induced hyperthermia.