Schmerz. 2009 Aug 20.
[Long-term treatment with oral ketamine : Case report of a female patient with therapy-resistant post-herpetic neuralgia.]
[Article in German]
neuralgia can lead to therapy-resistant neuropathic pain. We report the
case of a 74-year-old woman with postherpetic perineal neuralgia
resistant to opioids and antiepileptic drugs who has been successfully
treated with oral ketamine for 28 months. Pain scores were reduced by
more than 50%, despite dose reduction of other analgetic drugs.
Significant side effects have not yet been reported. Despite
"off-label" use, ketamine is an important third line option in cases of
therapy-resistant neuropathic pain.