Animal study

Title Average Ratingsort ascending
Combining agents that target the tumor microenvironment improves the efficacy of anticancer therapy. 90.00%
Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a 90.00%
NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell 90.00%
Vitamin D binding protein-macrophage activating factor (DBP-maf) inhibits angiogenesis and tumor growth in mice. 90.00%
Effects of a high molecular mass Convolvulus arvensis extract on tumor growth and angiogenesis. 90.00%
Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer. 90.00%
Opioid growth factor enhances tumor growth inhibition and increases the survival of paclitaxel-treated mice with squamous cell c 80.00%
A comparative evaluation of the influence of the complex drug Ukrain and its components on the effects of radiation 80.00%
Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytot..... 80.00%
Interaction between Ukrain and Naltrexone in the writhing syndrome test in mice 80.00%
Antinociceptive effect of ten day administration of Ukrain in mice and interaction of the treatment with morphine 80.00%
An orally active Amazonian plant extract (BIRM) inhibits prostate cancer growth and metastasis. 80.00%
Antiangiogenic potency of various chemotherapeutic drugs for metronomic chemotherapy. 80.00%
The dynamics of concentration of the main fluorescent component of Ukrain in the tissues and blood plasma of rats with W-256 ... 80.00%
Inhibitory effect of ginsenoside Rg3 combined with cyclophosphamide on growth and angiogenesis of ovarian cancer. 80.00%
Synergistic inhibitory effect of gemcitabine and angiotensin type-1 receptor blocker, losartan, on murine pancreatic tumor growt 80.00%
Low-dose chemotherapy combined with an antiangiogenic drug reduces human glioma growth in vivo. 80.00%
Hyperthermia improves the antitumour effect of metronomic cyclophosphamide in a rat transplantable brain tumour. 80.00%
Effective treatment of advanced human melanoma metastasis in immunodeficient mice using combination metronomic chemotherapy regi 80.00%
Metformin induces unique biological and molecular responses in triple negative breast cancer cells. 80.00%
The effect of whole-body hyperthermia combined with 'metronomic' chemotherapy on rat mammary adenocarcinoma metastases. 80.00%
Synergistic activity of PHY906 with capecitabine in pancreatic carcinoma. 80.00%
Endogenous opioids regulate expression of experimental autoimmune encephalomyelitis: a new paradigm for the treatment of multipl 80.00%
Effects of pomegranate juice on human cytochrome P450 2C9 and tolbutamide pharmacokinetics in rats. 75.00%
Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo 70.00%
A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses 70.00%
BET bromodomain inhibition as a therapeutic strategy to target c-Myc 70.00%
Gastric cancer originating from bone marrow-derived cells. 70.00%
Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemi 70.00%
Antiangiogenic effect of gemcitabine following metronomic administration in a pancreas cancer model. 70.00%
Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells. 70.00%
Cancer preventive effect of Morinda citrifolia (Noni). 70.00%
Effect of culture supernatant of Toxoplasma gondii on the proliferation and apoptosis of BGC-823 cells 70.00%
Sorafenib and radiation: A promising combination in colorectal and pancreas cancer 70.00%
Inhibitory effect of modified citrus pectin on liver metastases in a mouse colon cancer model. 70.00%
Low-dose metronomic cyclophosphamide treatment mediates ischemia-dependent K-ras mutation in colorectal carcinoma xenografts. 70.00%
New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163. 70.00%
Strong synergy of heat and modulated electromagnetic field in tumor cell killing. 60.00%
Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angio.. 60.00%
Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis. 60.00%
Increased Response to Ketamine Following Treatment at Long Intervals: Implications for Intermittent Use. 60.00%
Beta-solamarine: tumor inhibitor isolated from Solanum dulcamara. 60.00%
Tolerance to the anticonvulsant effect of morphine in mice: blockage by ultra-low dose naltrexone. 60.00%
Does the Ukrain preparation protect mice against lethal doses of bacteria? 60.00%
Theoretical grounds and experimental confirmation of the antiviral effect of the 60.00%
Highly efficacious nontoxic preclinical treatment for advanced metastatic breast cancer with metronomic UFT + CP 60.00%
Inhibition of spontaneous metastasis in a rat prostate cancer model by oral administration of modified citrus pectin. 60.00%
The ErbB inhibitors trastuzumab and erlotinib inhibit growth of vestibular schwannoma xenografts in nude mice: a preliminary stu 60.00%
Immunostimulatory effects of low-dose cyclophosphamide are controlled by inducible nitric oxide synthase. 60.00%
The influence of the novel drug Ukrain on hemo- and immunopoiesis at the time of its maximum radioprotective effect 60.00%
Low dose carboplatin combined with angiostatic agents prevents metastasis in human testicular germ cell tumor xenografts. 55.00%
Propolis Extract (Bio 30) Suppresses the Growth of Human Neurofibromatosis (NF) Tumor Xenografts in Mice 55.00%
Biological activity of some thiophosphamide derivatives of alkaloids with respect to influenza virus 50.00%
Inhibitive effect of artemether on tumor growth and angiogenesis in the rat C6 orthotopic brain gliomas model. 50.00%
Ukrain (NSC-631570) influences on bone status: a review. 50.00%
The ErbB inhibitors trastuzumab and erlotinib inhibit growth of vestibular schwannoma xenografts in nude mice: a preliminary 50.00%
Influence of Ukrain on the nuclear thyroid hormone receptors after short-term gamma-irradiation. 50.00%
Preclinical antitumor and antiangiogenic activity of a metronomic schedule of cisplatin against human transitional cell carcinom 50.00%
Some pharmacological properties of prolonged administration of Ukrain in rodents 50.00%
Circulating endothelial-cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy 50.00%
Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib. 50.00%
Modification of antinociceptive action of morphine by Ukrain in rodents 50.00%
A metronomic schedule of cyclophosphamide combined with PEGylated liposomal doxorubicin.... 50.00%
Evaluation of recombinant bacillus Calmette-Guerin expressing pertussis toxin in bladder cancer. 50.00%
Six-week treatment with Ukrain in rabbits. Part I: Morphological parameters 50.00%
Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water. 50.00%
Inhibition of angiogenesis of LCI-D20 hepatocellular carcinoma by metronomic chemotherapy of S-1 50.00%
A study of the influence of a novel drug Ukrain on in vivo effects of low-dose ionizing radiation 50.00%
Morphometric and kinetic analysis of the growth of experimental sarcoma-45 in the presence of Ukrain 50.00%
Enhancement of macrophage tumouricidal activity by the alkaloid derivative 40.00%
Improvement of cyclophosphamide activation by CYP2B6 mutants: from in silico to ex vivo. 40.00%
Anti-angiogenic effect of 5-Fluorouracil-based drugs against human colon cancer xenografts. 40.00%
Ukrain: acute toxicity after intravenous, intramuscular and oral administration in rats 40.00%
Combination antiangiogenic therapy: increased efficacy in a murine model of Wilms tumor. 40.00%
Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth. 30.00%
Effect of Ukrain on the efficacy of anti-epileptic drugs against maximal electroshock-induced seizures in mice. 30.00%
Cysteine proteinase inhibitor level in tumor and normal tissues in control and cured mice. 30.00%
The influence of Ukrain on the growth of HA-1 tumor in mice: the role of cysteine proteinases as markers of tumor malignancy 30.00%
Six-week treatment with Ukrain in rabbits. Part II: Serum levels of gonadal hormones 20.00%
The immunomodulating preparation Ukrain does not induce anaphylactic sensitization in mice and guinea pigs 20.00%
The influence of active hexose correlated compound (AHCC) on cisplatin-evoked chemotherapeutic and side effects in tumor-bearing 0.00%
Preliminary pharmacokinetic studies of Ukrain in rats 0.00%
Six-week treatment with Ukrain in rabbits. Part III: Serum levels of thyroid hormones 0.00%
Teratological evaluation of Ukrain in hamsters and rats 0.00%